How Perimenopause Shaped Perspectives on Life during the Pandemic: A Study on India's Working and Non-Working Women

The menopausal transition is a challenging phase in a woman's life and has been compounded by the COVID-19 pandemic. This study aimed to examine the association between meaning in life, quality of life, and satisfaction with life among perimenopausal women during the pandemic, as well as to determine if there was a difference in attitudes towards life between working and non-working perimenopausal women. The study sample consisted of 114 perimenopausal women, with 64 being employed and 50 being non-employed. A quantitative cross-sectional design was employed, and the results showed that satisfaction with life was positively correlated with both meaning in life and quality of life. Working perimenopausal women had a higher level of satisfaction with life (mean score of 63.24) as compared to non-working perimenopausal women (mean score of 50.14), but there was no significant difference in quality of life or meaning in life between the two groups. The study highlights the impact of various social and personal factors on how women perceive their lives during the pandemic and underscores the need for increased support and resources for perimenopausal women in the workplace. Additionally, promoting menopause awareness in general and in the workplace could help to reduce social barriers and improve women's perspectives on life, leading to an improvement in their overall quality of life and satisfaction with life. This study insisted on the need for giving importance to this stage in women's life-rather passing it just like that. Policy makers in the HR field should make a note to the finding and incorporate necessary amendment in terms of the female workforce.

Correction of menopausal disorders: New possibilities of menopausal hormone therapy

Determining the role of menopausal hormone therapy in the era of covid infection is an urgent task. The reasons for the lower rate of severe outcomes in women against the background of covid infection compared to men are currently being discussed. This is suggestive of the idea that the female body has the protection that accounts for this advantage. that Scientific literature data were reviewed to select the best combination of estrogen and progesterone when used as menopausal hormone therapy in the present setting. During the analysis of the literature on the use of estrogens and progestins as menopausal hormone therapy published in recent years, we used the following sources: PubMed, E-libary, Scopus. The body of material, which we studied, led us to a conclusion about the preference for the gestagen component when menopausal hormone therapy was prescribed. Gestagen should have the lowest risks in the development of thrombosis, as well as level the pronounced symptoms of peri- and postmenopause. According to the sources we studied and the authors’ own clinical experience, levonorgestrel-containing menopausal hormone therapy preparations have a high safety profileImproving physicians’ literacy about the criteria for prescribing menopausal hormone therapy, including drugs containing two components, estrogen and levonorgestrel in a cyclic regimen, will allow the use of hormone therapy in a wider range of patients in the perimenopausal and postmenopausal periods. © 2022, Remedium Group Ltd. All rights reserved.

Effects of Group and Individual Culturally Adapted Cognitive Behavioral Therapy on Depression and Sexual Satisfaction among Perimenopausal Women.

AIMS: Previous research has shown the efficacy of culturally adapted Cognitive Behavioral Therapy (CA-CBT) in reducing depression, yet its effect on increasing sexual satisfaction is not well documented. In this study, an embedded randomized controlled trial design was used to examine the effect of group and individual CA-CBT on depression and sexual satisfaction among perimenopausal women. METHOD: A total of 64 depressed Iranian perimenopausal women were randomly assigned to two formats of treatments; sixteen sessions of group CA-CBT and eight sessions of individual CA-CBT, as well as a waitlist control group. Depression and sexual satisfaction were measured using BDI-II and ENRICH, respectively, at T1 (pre-treatment), T2 (post-treatment) and T3 (follow-up). RESULTS: Repeated measures ANOVA indicated that the women who underwent both group and individual CA-CBT had effectively reduced depression and increased sexual satisfaction between pre-treatment and post-treatment, and it was sustained after six months of follow-ups with large effect sizes of significant differences (p < 0.001), but the control group did not. CONCLUSION: The results showed promising evidence for the efficacy of both treatment groups of CA-CBT for depression and sexual satisfaction among perimenopausal women. The population mental health burden among perimenopausal women may likely be reduced by propagating this effective treatment.

COVID-19 Outcomes in Postmenopausal and Perimenopausal Females: Is Estrogen Hormone Attributing to Gender Differences?

BACKGROUND: Globally, case fatality rate is more in males compared to females. Some studies have suggested. It is hypothesized that estrogen hormone may decrease susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS CoV-2.). OBJECTIVE: The objective of the study was to evaluate the gender differences in SARS CoV-2 outcomes and to analyze if there are any differences in outcomes in premenopausal females compared to postmenopausal females. MATERIALS AND METHODS: Patients tested positive for SARS CoV-2 through real-time reverse transcription-polymerase chain reaction by Thermo Fischer Taqpath assay approved by the Indian Council of Medical Research were included in the study. The data obtained was analyzed for the epidemiological, clinical, and laboratory characteristics from their medical records. RESULTS: The mortality rate in females was 12.6%, whereas mortality in males was 19.4%. In between-group analysis, 8.6% (16/185) of females died in premenopausal age group versus 12.8% (27/211) in postmenopausal group. The proportion of females who expired due to COVID significantly differ by age and postmenopausal status X2 (1, n = 293) = 7.2, the P value is 0.007. The difference is statistically significant at P < 0.05. Postmenopausal women were more likely to expire due to COVID-19 infection compared to premenopausal women. CONCLUSION: The mortality rate in postmenopausal age group was greater than mortality in premenopausal females emphasizing the protection provided by estrogens hormone in them. Postmenopausal women are also at higher risk of severe COVID-19 infection than premenopausal women. Mortality is greater in males compared to females, further strengthening the role of estrogens.

Peri and postmenopausal women in times of coronavirus pandemic.

The global pandemic of novel coronavirus disease 2019 has transformed health care around the world. Physicians and health-care providers face a great challenge regarding medical management notably women going through the perimenopause or those who are postmenopausal, some of them with medical comorbidities. Cancer care and screening have been disproportionately affected by COVID-19 which may have direct effects on oncological treatments. Furthermore, a major concern during the periods of social isolation involves the relationship between couples. Our attention on health and health care during this unprecedented crisis should reflect this reality, and I believe we can learn extraordinary lessons.